Neo
#102
I do vinegar especially if I can ahead of any higher carb diet I can’t “control” in a social context.
I wonder if it is healthy to keep regularly lowering one’s ph - but I haven’t had time to look into it. Anyone have an idea about that?
(Also may have a negative impact on teeth in the medium to long run)
1 Like
medaura
#103
The probiotic seems priced to part fools from their money. But what’s to stop people from pooling a bit of cash to buy a single bottle, then mailing a handful of pills to each contributor, for them to use to grow more of that probiotic in yoghurt or a sugary medium, in perpetuity? I grow water kefir (well I just killed my culture but that’s another story) so how is planting and growing these magic beans any different? It would take a special kind of idiot to buy those pills on the regular, methinks.
7 Likes
I like your creativity! Any yoghurt experts here… I wonder if there are any issues that might limit the feasibility of this idea?
2 Likes
Bicep
#105
Does the label list the strains inside? A mix will shift over time, with some of the strains taking over, others disappearing. But still very easy to decrease cost by a factor of at least 10, maybe way more. Also if it’s a mix some of them may need 110 degrees, others maybe 90 so it may work and it may not.
5 Likes
Bicep
#107
Wow, pretty good stuff from what I’ve read (Gundry,Davis). I’d love it if it was cheap. So did he do a test of his stool to find out he needs more SCFA? Or any kind of test to see what he already has? I don’t follow him at all. Just because my time is limited, not because he’s boring or anything.
I’ll work on this for awhile, thanks Neo
1 Like
Neo
#108
Awesome! Yes, it looks good to me too. (Though I agree that is is pricey).
Dr. Attia did not mention/discuss this in depth (yet) so did not go into to microbiome testing, etc. but hopefully he is doing it in a systematic way and will come back and report more on it in the future.
Bicep
#109
It looks like you are better off taking inulin than you are supplementing the actual Akkermansia muciniphila. Also it’s much much cheaper.
3 Likes
I lost some of my enthusiasm for inulin after seeing this research…
A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other parts of the body, according to a preclinical study from researchers in the Friedman Center for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell’s Ithaca campus.
The study, published Nov. 2 in Nature, found that dietary inulin fiber alters the metabolism of certain gut bacteria, which in turn triggers what scientists call type 2 inflammation in the gut and lungs. This type of inflammation is thought to have evolved in mammals chiefly to defend against parasitic worm (“helminth”) infections, and is also part of normal wound-healing, although its inappropriate activation underlies allergies, asthma and other inflammatory diseases.
There’s a lot to think about here, but, in general, these findings broaden our understanding of the relationship between diet, immunity, and the normally beneficial microorganisms that constitute our microbiota and colonize our bodies."
Dr. David Artis, Study Co-Senior Author, Director, Friedman Center for Nutrition and Inflammation and the Michael Kors Professor of Immunology at Weill Cornell Medicine
“Extrapolation to humans, either in terms of biological relevance or possible interventions, remains limited. However, the study does raise intriguing new insights that will require replication and further research toward mechanisms of action,” he told Medical News Today .
Journal Article (paywalled)
https://www.nature.com/articles/s42255-022-00692-9
13 Likes
约瑟夫
#111
Bicep
#112
Yes, and the pendulum has half a gram of inulin in each capsule. It’s more than $2 per capsule and the inulin (which is close to free at that rate) does more good than the akkermansia. I suppose there are people that have none, and they should try to get it established, but from what I’ve read it is out there, just not well fed.
1 Like
Neo
#113
Anyone know how this could be measured/monitored (outside of a research lab setting)?
约瑟夫
#115
Make grow your own and use your own insulin,.
Neo
#116
@Bicep @Joseph @medaura @RapAdmin any perspective on above?
Neo
#117
Thanks. Do issue is that my crp tends to be below the lower limit/bound.
medaura
#118
I’m no expert in growing micro critters but I do dabble. One user mentioned upthread that the composition would change over time since the growing conditions will favor one strain over the others. So I think every now and then we’d need to reset the batch. This can be easily done by buying a bottle and refrigerating it only to pull out pills every month or biweekly to grow in a medium.
As far as how well those strains will line your gut, I think it’s primarily a function of your fiber intake.
2 Likes
medaura
#119
Hence the need for using the HS version. If your levels are even below the high sensitivity version then it’s all good news for you.
medaura
#121
Well that’s a good problem to have 