#82

Here are my latest cholesterol and inflammation scores after being back in rapamycin for the last 4-5 months. My Lipoprotein(a) result of 84.20 nmol/L seems to place me in a grey zone? When combined with Apolipoprotein B of 0.92 g/L just within “normal” range I think I need to take some action.

I hear some folks here have had good success with BrilloEZ combo of ezetimibe and bempedoic acid?

Cholesterol Status
Total Cholesterol X 5.01 mmol/L
LDL Cholesterol X 3.02 mmol/L
Non HDL Cholesterol 3.46 mmol/L
HDL Cholesterol 1.55 mmol/L
Total Cholesterol : HDL 3.23 Ratio
Triglycerides 0.97 mmol/L
Triglyceride : HDL 0.6 Ratio
Apolipoprotein A1 1.44 g/L
Apolipoprotein B 0.92 g/L

Lipoprotein(a) 84.20 nmol/L
A result of >75nmol/L is considered to reflect
increased risk (Framingham data).
(Range: < 75)

ApoB : ApoA ratio 0.6 ratio (Range: < 0.7)

Inflammation
CRP HS 1.47 mg/L (Range: < 3)

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#84

Our cholesterol and inflammation results look quite similar @Michele_Watson although I do have a much lower lp(a). Having reviewed the threads on here I have placed an order with Maulik for BrilloEZ which contains Bempedoic acid (180mg) + Ezetimibe (10mg). It can take 2-3 months to have full effect. I will report back here when I get my next blood test but could be a while.

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#85

Thank you! I really appreciate that.

I might try the BrilloEX (wonder if anyone on this thread is from Australia). I weigh 53 kgs and female (64 years old) I wonder if that might mean adjustments to dose? Low estrogen and low thyroid (no meds as yet) but these also contribute to my current cardio status.

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#86

Pelarcarsen phase three participant attributes -

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About point 9 (interim analyses):

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So even if finality isn’t expected to be reached until next year, maybe there will be some fireworks in the interim.

https://www.sciencedirect.com/science/article/pii/S0002870325001012

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#87

Having a low waist:hip ratio (i.e. low visceral fat) eliminated the increased CVD risk from elevated Lp(a)???

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#88

Wow.

Haven’t looked into it, but see this one somewhat related

Lipoprotein(a) and Body Mass Compound the Risk of Calcific Aortic Valve Disease

https://www.jacc.org/doi/10.1016/j.jacc.2021.11.043?

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#89

Am very thin (0.82 WHP ratio) - so reassuring - tho will see what the stress echocardiogram test shows soon. My Lp(a) is 187. Today I started on a new bergamot formulation (Dr Mercola) and berberine. I am going to take a few natural PCSK9 inhibitors for now…for those that do not know how to calculate just measure waist then hip- then divide the waist by the hip measurement.

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