I’m getting more and more over the average fringe person to be honest. I just want to learn about regular old clinical trials and such things. I think Bryan is much better than the other ones though but I don’t know him.

Next to Johnson is a very fit man in his early 50s. He also wears a “Don’t Die” T-shirt and has the blank, unsmiling blue eyes and faux-casual cadence of an experienced salesman. This is Johnson’s “lead doctor,” Mike Mallin—Dr. Mike for short. Once an emergency room physician, he “left academics for private practice in 2017” and now runs a concierge medical service called Wild Health.

https://www.wildhealth.com/team/mike-mallin

https://www.linkedin.com/in/mike-mallin-a68a823/

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The number of doctors and clinics in the longevity space is growing quite rapidly. So far most seem to be taking advantage of people with little knowledge to charge outrageous prices.

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Either that or doctors who “prescribe” you worthless lifestyle changes.

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From the tankie article. Will be interesting to see if this gets any traction.

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@amuser This sounds quite good. If it looks legit I’ll likely nominate some of my key foods and see if I can be part of getting the flywheel going.

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I’m not clear on the concept of how (when you have $300 Million in assets) you can justify not investing in longevity research, when your entire messaging is all around “Don’t Die”. Does anyone else have problems with this?

Basically, you’re just a marketing organization then…

Source: https://x.com/bryan_johnson/status/1895986897660625143

I’m with Aubrey on this…

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Agreed

‘This moment is not about solving aging, that will take time’
As you said, his entire message is about not aging, so this seems like gibberish.

‘Technology follows’
HUH? I’ve never seen anyone so wired up to tech.

No one is obligated to fund anything but his reasons for not doing so are nonsensical.

Dear Bryan, I always defend you… stop making it so hard!!!

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Sorry, but Bryan can’t be defended on this. He should at least pony up $500,000 annually (0.16% of his NW) for research. For him, that’s a rounding error.

The ITP would be a good place to invest. Trial one drug a year.

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Hear, hear. If I was a billionaire, I’d fund such research with vast sums - you can’t take it with you, so why not. I really don’t get it with some of these guys for whom a few million $ is nothing, their fortune makes that much just passively in a day. I’d throw cash at a lot of these deserving studies that can’t get financed otherwise. Not even for myself, but out of pure intellectual curiosity. But hey, maybe that’s why they’re billionaires and I’m not🤣.

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So true! Sadly the richest ones are even actively destroying the NIH, the NSF and scientific research in general. Even the ITP might be cancelled. They probably think the mice are too woke.

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Bryan Johnson at this week’s SXSW

Don’t Die with Bryan Johnson | SXSW LIVE

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My Blueprint co-founder Kate has had depression for about 4 years. Not wanting to start anti-depressants, she tried a groundbreaking new 5-day TMS protocol called SAINT.

image
https://x.com/bryan_johnson/status/1902044120807567436#m

HBOT looks like a legitimate therapy for different conditions.

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N=1 is not a well-powered study. I’ll wait for the papers :wink:

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HBOT is FDA approved for about a dozen different diseases or conditions.

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yes, now if only I had a $100,000 for a chamber

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I wonder why Bryan Johnson doesn’t include more members of his team in these tests; it would be more convincing.

Later, he says that there will soon be clinics and certified professionals by Don’t Die. That significantly undermines the seriousness of his intentions since, to many—including myself—it looks more like advertising than scientific dissemination.

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Impressive results and a glowing review for HBOT. I will say that I’m skeptical of the microbiome/SCFA results. I’ve sent out samples from the exact same stool to two different labs and one showed 0 across the various SCFA and the other showed in the normal range. There were also many inconsistencies between the bacteria found, some were high on one test and low on the other. So I would take those results with a grain of salt.

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I’ll throw out there that I’ve done mHBOT at 1.3ATA for years and it does seem to increase serum VEGF. My numbers tend to be high-normal or just above the range when I’m using it consistently, and when I recently tested after a month away from it, VEGF was low-normal. Specifically, 170 pg/mL on January 2nd and 22 pg/mL on February 3rd with a range of 0 - 115 (this was the highest I’ve ever seen it, usually hovers around 100-120).

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