I know that Citrillune has its fans and papers supporting its use. Low dose arginine has worked for me.

I think that Kaatsu claims that their blood flow restriction bands increase VEGF
“Data from research at the University of Tokyo Medical School Hospital’s 22nd Century Medical Center from the Ischemic Circulation Physiology Department found that KAATSU leads to the secretion of Vascular Endothelial Cell Growth Factor (VEGF).”

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maybe natto
“antithrombotic, antihypertensive, anticoagulant, anti-atherosclerotic, and neuroprotective effects”

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Stephanie Seneff is open minded and brilliant and I had heard her talk about how sulfate makes the blood flow. Cholesterol sulfate deficiency is the cause of heart disease. This is what she said and I’ve spent years looking for a better, more thorough explanation of this. So here are a couple videos, first one is Stephanie herself, second is a student of hers or at least a big fan and he spends the time to explain in a way that a less educated person such as myself can understand. Talking again about Zeta potential is important and a long discussion about the glycocalyx and it seems to come down to Sulfate.

And I’m really wondering whether DMSO does it’s magic by improving blood flow by hacking the sulfate system. Have they tried DMSO in the million molecule challenge, or on mice anywhere. I know it’s too much to ask for the ITP.

This is the TED talk I heard 8 years ago and it’s very similar to the talk above by her fan, but he does a better job of the explanation:

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A Healthy micro-vasculature is a factor that attenuates the aging process of organs. Historically, there has been more focus on the macro-circulation and arteriosclerosis. There are related links in this thread. I hope this Isareli research gets more attention.

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I’ve never heard of this woman, but it seems odd that she’s a computer scientist. I have lots of friends who are computer scientists out of MIT, and while they are very smart people I wouldn’t trust anything they said about health issues. The issue of her discussion cholesterol sulfates seems more than a little out of her lane of expertise…

Seneff and her MIT colleagues have also published on the health impacts of fat and cholesterol consumption in America. Based on this work, Seneff claimed that Americans are suffering from a cholesterol deficiency, not an excess.[20][21] In 2014–2016 Seneff was proposed as an expert witness for litigators seeking damages from Pfizer associated with their cholesterol drug Lipitor,[22] but the court dismissed the claim largely because Seneff lacked expert status and failed to provide credible evidence linking Lipitor to any specific harm.[23]

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Stephanie Seneff? No thank you. There are much better sources of information and science. Her work has nothing to do with established methods of science.

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Another n = 1 but beetroot powder, added to my breakfast regime, has helped and I suspect has an indirect NO benefit

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I believe that one of the mechanisms of action of autologous plasma injections is by increasing VEGF.

I take citrulline daily as well as Captopril. I used to alternate daily between Losartan and Enalapril to try to capture the benefits of both. When I told my GP I thought he was going to have kittens in the corner! :)) LOL
Nowadays it’s just Captopril. It’s crazy cheap where I am, too; about $1/pack.

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She makes wild claims and has ZERO credibility.

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The phrase “structured water” says all you need to know about her lack of credibility.

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When I see “structured water” I’m not going to listen to that person.

If they are willing to promote a scam like that, there is no credibility left in that person. While they may also promote something else that has validity, by promoting 1 scam it taints them as an unreliable source of information.

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The AHA begs to differ.

https://www.ahajournals.org/doi/epub/10.1161/01.CIR.103.16.2032

Plasma levels of cholesterol sulfate are elevated in clinical conditions such as hypercholesterolemia and liver cirrhosis.11 Because cholesterol sulfate is present in the atherosclerotic lesions of human aorta4 and plasma levels are increased in hypercholesterolemia,11 cholesterol sulfate may play a role in atherosclerosis. In this study, we show that cholesterol sulfate is a substrate for platelet adhesion and may thereby contribute to the prothrombotic potential of atherosclerotic lesions.

Due process. I’ve read the AHA article. Now to watch your video.

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8:22. Endothelial nitric oxide synthase performs the magic.

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Her recommendations:

  1. Eat organic
  2. Get lots of dietary sulfur (cruciferous vegs)
  3. Get out in the sunlight
  4. Get grounded

No need for structured water (whatever that is). Citrulline, cruciferous vegs, and sunlight will do.

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Well I hope she’s wrong about glyphosate. She really hates it. I hope she’s right about cholesterol. Also it would be good to find out whether vaccines improve all cause mortality. Big controversy there.

I admit I didn’t do even the quick check you guys did to find out her specialty. I was too busy trying to decide whether it makes sense that electrical charge pulls the blood. It may be true, but seems a crazy method because the charge has to be brought back eventually. Nothing is free.

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Bicep, if even Trump is on rosuvastatin what makes you so convinced that your alternative source is right?

I don’t think politicians necessarily tell the truth about their medical treatment, I wouldn’t go by anybody in politics (on either side) when deciding what I should do. Trump supposedly took the jab. Did I take the jab? They do things that support the positions that they take for the people. There may be honest politicians but I’m not capable of telling the difference.

For me I go more by mechanistic arguments even though our understanding of the biology is not sufficient. I know these arguments are just stories about what certain people think. They’re constantly being revised. I can’t help it, I love the stories and for me they’re persuasive.

It has always seemed to me that if you need a million or a hundred thousand people in a study to figure out what difference a drug makes then it’s not much of a difference. People argue about whether P should be .01 or .0001. To me the statistics , which should clarify, really could be used to obfuscate. And when big expensive studies are done, the company paying is able to move people and things around to cheat. So to me it’s not gospel, it’s more like the word on the street in the stock market. And if you keep betting on the word on the street you can lose all your money. Gotta use your own brain even if it’s not so good.

But 60% of Republicans or so are completely opposed to taking the vaccine and I remember Trump being booed for that in the past in one of his rallies.

People argue about whether P should be .01 or .0001. To me the statistics

Having a clear cutoff makes sense as otherwise any minor deviation by chance could be interpreted as a result.

Just curious @Bicep what would be required to convince you to start taking a statin or bempedoic acid, ezetimibe, and a PCSK9 inhibitor? What evidence would you need?

Like, you’re looking at a pack of bempedoic acid + ezetimibe, and another package of PCKS9 inhibitors. What goes into your mind “these will help me”, or “these won’t”? How do you determine which category they are in? What is required for “these will help me” category?

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