Bicep
#132
Wow it took a full month to get the test back. Akkermansia was pretty good:
Not optimal, but I at least have some to work with. Also Thorne shows you your SCFA:
which I though were pretty good, though they thought lactate was off some. Other than that I only got a bad score for disbiosis something like what Len got. Maybe we all have some disbiosis. I don’t know what to do, I suppose look through their expensive stuff and try to improve.
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Bicep
#134
That was Thorne. You can see them at thorne.com.
It’s a fairly expensive test, like $180 if I remember right.
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You can focus on just optimizing fiber intake and leave the rest to God.
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约瑟夫
#136
Why do people have to bring ideology into science?
Bicep
#138
I understand the strategy. My second daughter who just had her 5th home birth would agree this is the way to go. My tendency is to cheat instead. I can’t help myself this time of year. I use 25 gm psillium in my morning smoothie, add a little alpha cyclodextrin and maybe some inulin later. So I’m using processed ingredients from India.
I much prefer when I can forage in the garden, but the only thing I have now that could help is Jerusalem Artichoke. I can harvest a 5 gallon pail in about 10 minutes effort, but my gut can only take about a couple tablespoons worth per day without revolting. Beans are good, but I’m still trying to be Keto. So I’m stuck with cheating.
3 Likes
There’s fructooligosaccharides, human milk oligosaccharides, inulin, resistant starch, you name it. I’m saying you can cheat with prebiotic supplements as they’re more logical and much cheaper than just dumping probiotics into the gut. Oh also various poly phenols that it seems as though the critters you want to feed really thrive on: green tea and pomegranate extracts. Or mixed frozen fruits and veggies in a smoothie. Akkermansia also seem to love rhubarb. And Jerusalem Artichoke is real good for the liver. Maybe make a tea out of the surplus that you can chow down.
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I never heard anything about supplementing this in adults. Can you share more color to it?
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L_H
#141
This is my approach too (excluding human milk!), and you can add fasting and anthocyanins to the mix. I can see why someone might be tempted to use a probiotic to guarantee a starter a dose. But surely we’ve learned that prebiotics rule when it comes to long-term sustainable benefits. And most akkermansia boosting foods have multiple other benefits.
Intermittent fasting, Commentary: Intermittent Fasting and Akkermansia Muciniphila Potentiate the Antitumor Efficacy of FOLFOX in Colon Cancer - PMC
Rhubarb https://www.tandfonline.com/doi/full/10.1080/19490976.2023.2178796#:~:text=We%20have%20previously%20demonstrated%20that,the%20abundance%20of%20Akkermansia%20muciniphila.
Pomegranates Pomegranate ellagitannins stimulate the growth of Akkermansia muciniphila in vivo - PubMed
**FOS rich foods (**red onions, garlic Jerusalem artichokes, pulses, unripe bananas) Strategies to promote abundance of Akkermansia muciniphila, an emerging probiotics in the gut, evidence from dietary intervention studies - PMC.
Pycnogenol Highlighting the Relevance of Gut Microbiota Manipulation in Inflammatory Bowel Disease - PMC
And if you want a boost there’s always metformin, berberine etc.
It feels like akkermansia probiotics are largely unnecessary?
3 Likes
I would use the probiotics for a month or two then support with prebiotics. So not sure I’d say they’re useless because some people have very poor initial combo of gut flora so it might be good to reintroduce specific strains. But for ongoing maintenance the way to go would be the right fiber mix.
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To be honest I don’t know much about it but they kept popping up as recommended products on Amazon after purchasing fructooligosaccharides and there seemed to be very positive feedback overall.
https://a.co/d/0GybdYp
2 Likes
Neo
#144
And @L_H seems good, but one might want to include TESTING in this program to know the effects vs just flying based on feelings
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Neo
#145
Not sure how relevant / similar, but Blueprint has added this for BJ:
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ng0rge
#146
Looks interesting. When I did a search, it came up as being in Nestle infant formula.
Wonder how similar it is to colostrum, which you can also buy:
https://www.amazon.com/WONDERCOW-Colostrum-Supplement-Concentrated-Unflavored/dp/B0BRTHDKDR
For Akkermansia, my guess is that if you don’t have glucose issues and/or aren’t overweight, your akkermansia levels are probably normal - assuming you’re following good dietary recommendations for gut health (fiber, yogurt, other fermented foods, kombucha maybe). I’m always looking for something promising and not too expensive.
Colostrum sold is of bovine origin. These are specific compounds found in human milk though it seems they’re being produced artificially (I should hope no women were milked for the Amazon supplement 
).
4 Likes
Bicep
#148
Yes, it says right on it that it is made by fermentation. I have tried this stuff before. My brother has Crohn’s and it is supposed to help that. This form looked like it was a buck a day. I don’t think the other stuff I’ve tried was that expensive, but I’m pretty sure it was the same stuff.
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ng0rge
#149
Is that enough color? Or would you like a picture?
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Perhaps a new untapped market opportunity, so to speak.
And yes, this seems like an area ripe for humor, and perhaps even a riff off that old saying about a “why buy the cow when the milk is free”… but I’m not going there. Only the brave will tread in that direction.
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