#21

It depends on the body weight. Empirically, totally without scientific basis: I used 1 mg/ week for less than 100 lb, and 2 mg/ week for 100-160 lb. Then titrate based on side effect and response. For dementia, families are reporting that the patients became mentally brighter (more responsive) but we have not seen Oliver Sacks “Awakening” like effect. But I have only tried a handful of neuro patients.

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#22

@TARM, it’s indeed tragic especially when a person is in a persistent vegetative state and is kept “alive” on a ventilator by their family for years (not exaggerating). Unfortunately it happens more than people realize.

#23

The argument in favour of this is that the future is moving towards us at the speed of a concord. In 3 years or 4 to 5 years we will have cures for diseases we don’t have today We have alpha fold 3 just released We have singularity happening soon digital super intelligence, many new discoveries on the molecular and biological levels will be made. Kurzeil purports that if you stay alive for the next 8 to 9 years you will be able to reach longevity escape velocity and freeze the ageing process on a molecular level.

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#24

There are still a couple hard steps to overcome from current LLMs to a true AGI.

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#25

@Martin_Gluckman,

Update please. Did your patient take RAPA and what were the results?

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